iPSC retinal modelling
Strengthen efficacy and safety evidence using relevant preclinical models and translational data.
Offer overview
What this offer helps you achieve
Strengthen efficacy and safety evidence using relevant preclinical models and translational data.
Scientific and technical scope
The iPSC platform provides technological and scientific support to teams, who carry a project integrating human iPS cells. It relies on expertise and specific know-how in: - Human iPS cell cultures - Gene editing by different CRISPR/Cas9 strategies. - Differentiation of human iPS cells towards the retinal lineage: retinal organoids, retinal ganglion cells, photoreceptors and retinal pigmented epithelial cells. - Characterization of human iPS-derived retinal cells and organoïds.
Capabilities mobilised
Therapeutic areasTherapeutic target discoveryValidation using preclinical modelsBiomarkersPlatforms
Application fields
Genetic and rare diseasesOphthalmology
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